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Concise Total Synthesis of Lundurines A–C Enabled by Gold Catalysis and a Homodienyl Retro-Ene/Ene Isomerization

[Image: see text] The total synthesis of lundurines A–C has been accomplished in racemic and enantiopure forms in 11–13 and 12–14 steps, respectively, without protection/deprotection of functional groups, by a novel tandem double condensation/Claisen rearrangement, a gold(I)-catalyzed alkyne hydroar...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Kirillova, Mariia S., Muratore, Michael E., Dorel, Ruth, Echavarren, Antonio M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819460/
https://ncbi.nlm.nih.gov/pubmed/26963149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b01428
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