A novel fibroblast growth factor receptor 1 inhibitor protects against cartilage degradation in a murine model of osteoarthritis

The attenuated degradation of articular cartilage by cartilage-specific deletion of fibroblast growth factor receptor 1 (FGFR1) in adult mice suggests that FGFR1 is a potential target for treating osteoarthritis (OA). The goal of the current study was to investigate the effect of a novel non-ATP-com...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Xu, Wei, Xie, Yangli, Wang, Quan, Wang, Xiaofeng, Luo, Fengtao, Zhou, Siru, Wang, Zuqiang, Huang, Junlan, Tan, Qiaoyan, Jin, Min, Qi, Huabing, Tang, Junzhou, Chen, Liang, Du, Xiaolan, Zhao, Chengguang, Liang, Guang, Chen, Lin
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819196/
https://ncbi.nlm.nih.gov/pubmed/27041213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24042
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