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Topographic expression of the Hippo transducers TAZ and YAP in triple-negative breast cancer treated with neoadjuvant chemotherapy

BACKGROUND: The Hippo signaling acts as a tumor-suppressor pathway that negatively regulates TAZ and YAP. Increasing evidence supports the activation of TAZ and YAP in breast cancer. Moreover, the Hippo pathway is involved in the biology of non-neoplastic cells residing in the tumor microenvironment...

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Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Vici, Patrizia, Ercolani, Cristiana, Di Benedetto, Anna, Pizzuti, Laura, Di Lauro, Luigi, Sperati, Francesca, Terrenato, Irene, Gamucci, Teresa, Natoli, Clara, Di Filippo, Franco, Botti, Claudio, Barba, Maddalena, Mottolese, Marcella, De Maria, Ruggero, Maugeri-Saccà, Marcello
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818869/
https://ncbi.nlm.nih.gov/pubmed/27039292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0338-7
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