Expression of phosphorylated Hippo pathway kinases (MST1/2 and LATS1/2) in HER2-positive and triple-negative breast cancer patients treated with neoadjuvant therapy

The Hippo kinases MST1/2 and LATS1/2 inhibit the oncoproteins TAZ/YAP and regulate T cell function. Hippo kinases also cooperate with the ATR-Chk1 and ATM-Chk2 pathways, central orchestrators of the DNA damage response (DDR). We hypothesized that MST1/2 and LATS1/2 localization differently impacts t...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Ercolani, Cristiana, Di Benedetto, Anna, Terrenato, Irene, Pizzuti, Laura, Di Lauro, Luigi, Sergi, Domenico, Sperati, Francesca, Buglioni, Simonetta, Ramieri, Maria Teresa, Mentuccia, Lucia, Gamucci, Teresa, Perracchio, Letizia, Pescarmona, Edoardo, Mottolese, Marcella, Barba, Maddalena, Vici, Patrizia, De Maria, Ruggero, Maugeri-Saccà, Marcello
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499753/
https://ncbi.nlm.nih.gov/pubmed/28387539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1312230
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