Topographic expression of the Hippo transducers TAZ and YAP in triple-negative breast cancer treated with neoadjuvant chemotherapy

BACKGROUND: The Hippo signaling acts as a tumor-suppressor pathway that negatively regulates TAZ and YAP. Increasing evidence supports the activation of TAZ and YAP in breast cancer. Moreover, the Hippo pathway is involved in the biology of non-neoplastic cells residing in the tumor microenvironment...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Vici, Patrizia, Ercolani, Cristiana, Di Benedetto, Anna, Pizzuti, Laura, Di Lauro, Luigi, Sperati, Francesca, Terrenato, Irene, Gamucci, Teresa, Natoli, Clara, Di Filippo, Franco, Botti, Claudio, Barba, Maddalena, Mottolese, Marcella, De Maria, Ruggero, Maugeri-Saccà, Marcello
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818869/
https://ncbi.nlm.nih.gov/pubmed/27039292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0338-7
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