miR‐515‐5p controls cancer cell migration through MARK4 regulation

Here, we show that miR‐515‐5p inhibits cancer cell migration and metastasis. RNA‐seq analyses of both oestrogen receptor receptor‐positive and receptor‐negative breast cancer cells overexpressing miR‐515‐5p reveal down‐regulation of NRAS, FZD4, CDC42BPA, PIK3C2B and MARK4 mRNAs. We demonstrate that...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Pardo, Olivier E, Castellano, Leandro, Munro, Catriona E, Hu, Yili, Mauri, Francesco, Krell, Jonathan, Lara, Romain, Pinho, Filipa G, Choudhury, Thameenah, Frampton, Adam E, Pellegrino, Loredana, Pshezhetskiy, Dmitry, Wang, Yulan, Waxman, Jonathan, Seckl, Michael J, Stebbing, Justin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818771/
https://ncbi.nlm.nih.gov/pubmed/26882547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540970
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