Growth Arrest-Specific Transcript 5 Associated snoRNA Levels Are Related to p53 Expression and DNA Damage in Colorectal Cancer

BACKGROUND: The growth arrest-specific transcript 5 gene (GAS5) encodes a long noncoding RNA (lncRNA) and hosts a number of small nucleolar RNAs (snoRNAs) that have recently been implicated in multiple cellular processes and cancer. Here, we investigate the relationship between DNA damage, p53, and...

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Detalhes bibliográficos
Main Authors: Krell, Jonathan, Frampton, Adam E., Mirnezami, Reza, Harding, Victoria, De Giorgio, Alex, Roca Alonso, Laura, Cohen, Patrizia, Ottaviani, Silvia, Colombo, Teresa, Jacob, Jimmy, Pellegrino, Loredana, Buchanan, Gordon, Stebbing, Justin, Castellano, Leandro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057237/
https://ncbi.nlm.nih.gov/pubmed/24926850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098561
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