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Upstream ORFs are prevalent translational repressors in vertebrates

Regulation of gene expression is fundamental in establishing cellular diversity and a target of natural selection. Untranslated mRNA regions (UTRs) are key mediators of post‐transcriptional regulation. Previous studies have predicted thousands of ORFs in 5′ UTRs, the vast majority of which have unkn...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Johnstone, Timothy G, Bazzini, Ariel A, Giraldez, Antonio J
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818764/
https://ncbi.nlm.nih.gov/pubmed/26896445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592759
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