AMP-Activated Protein Kinase and Glycogen Synthase Kinase 3β Modulate the Severity of Sepsis-Induced Lung Injury

Alterations in metabolic and bioenergetic homeostasis contribute to sepsis-mediated organ injury. However, how AMP-activated protein kinase (AMPK), a major sensor and regulator of energy expenditure and production, affects development of organ injury and loss of innate capacity during polymicrobial...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Med
Hauptverfasser: Liu, Zhongyu, Bone, Nathaniel, Jiang, Shaoning, Park, Dae Won, Tadie, Jean-Marc, Deshane, Jessy, Rodriguez, Cilina Ann, Pittet, Jean-Francois, Abraham, Edward, Zmijewski, Jaroslaw W
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Feinstein Institute Press 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818252/
https://ncbi.nlm.nih.gov/pubmed/26650187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00198
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