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Nuclear accumulation of glycogen synthase kinase-3 during replicative senescence of human fibroblasts
Activation of the tumor suppressor protein p53 contributes to cellular senescence. As glycogen synthase kinase-3 (GSK3) was recently found to interact with p53 and contribute to the actions of p53, this study examined whether GSK3 accumulated in the nucleus and associated with p53 in senescent cells...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1931580/ https://ncbi.nlm.nih.gov/pubmed/15379854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9728.2004.00117.x |
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