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Nuclear accumulation of glycogen synthase kinase-3 during replicative senescence of human fibroblasts

Activation of the tumor suppressor protein p53 contributes to cellular senescence. As glycogen synthase kinase-3 (GSK3) was recently found to interact with p53 and contribute to the actions of p53, this study examined whether GSK3 accumulated in the nucleus and associated with p53 in senescent cells...

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Detalhes bibliográficos
Main Authors: Zmijewski, Jaroslaw W., Jope, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1931580/
https://ncbi.nlm.nih.gov/pubmed/15379854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9728.2004.00117.x
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