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AMP-Activated Protein Kinase and Glycogen Synthase Kinase 3β Modulate the Severity of Sepsis-Induced Lung Injury

Alterations in metabolic and bioenergetic homeostasis contribute to sepsis-mediated organ injury. However, how AMP-activated protein kinase (AMPK), a major sensor and regulator of energy expenditure and production, affects development of organ injury and loss of innate capacity during polymicrobial...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Liu, Zhongyu, Bone, Nathaniel, Jiang, Shaoning, Park, Dae Won, Tadie, Jean-Marc, Deshane, Jessy, Rodriguez, Cilina Ann, Pittet, Jean-Francois, Abraham, Edward, Zmijewski, Jaroslaw W
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818252/
https://ncbi.nlm.nih.gov/pubmed/26650187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00198
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