Functional Stability of the Human Kappa Opioid Receptor Reconstituted in Nanodiscs Revealed by a Time-Resolved Scintillation Proximity Assay

Long-term functional stability of isolated membrane proteins is crucial for many in vitro applications used to elucidate molecular mechanisms, and used for drug screening platforms in modern pharmaceutical industry. Compared to soluble proteins, the understanding at the molecular level of membrane p...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Hansen, Randi Westh, Wang, Xiaole, Golab, Agnieszka, Bornert, Olivier, Oswald, Christine, Wagner, Renaud, Martinez, Karen Laurence
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817975/
https://ncbi.nlm.nih.gov/pubmed/27035823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150658
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