Functional Stability of the Human Kappa Opioid Receptor Reconstituted in Nanodiscs Revealed by a Time-Resolved Scintillation Proximity Assay

Long-term functional stability of isolated membrane proteins is crucial for many in vitro applications used to elucidate molecular mechanisms, and used for drug screening platforms in modern pharmaceutical industry. Compared to soluble proteins, the understanding at the molecular level of membrane p...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Hansen, Randi Westh, Wang, Xiaole, Golab, Agnieszka, Bornert, Olivier, Oswald, Christine, Wagner, Renaud, Martinez, Karen Laurence
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817975/
https://ncbi.nlm.nih.gov/pubmed/27035823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150658
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