Pharmacological Modulation of Photoreceptor Outer Segment Degradation in a Human iPS Cell Model of Inherited Macular Degeneration

Degradation of photoreceptor outer segments (POS) by retinal pigment epithelium (RPE) is essential for vision, and studies have implicated altered POS processing in the pathogenesis of some retinal degenerative diseases. Consistent with this concept, a recently established hiPSC-RPE model of inherit...

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發表在:Mol Ther
Main Authors: Singh, Ruchira, Kuai, David, Guziewicz, Karina E, Meyer, Jackelyn, Wilson, Molly, Lu, Jianfeng, Smith, Molly, Clark, Eric, Verhoeven, Amelia, Aguirre, Gustavo D, Gamm, David M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2015
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817951/
https://ncbi.nlm.nih.gov/pubmed/26300224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.141
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