Pharmacological Modulation of Photoreceptor Outer Segment Degradation in a Human iPS Cell Model of Inherited Macular Degeneration

Degradation of photoreceptor outer segments (POS) by retinal pigment epithelium (RPE) is essential for vision, and studies have implicated altered POS processing in the pathogenesis of some retinal degenerative diseases. Consistent with this concept, a recently established hiPSC-RPE model of inherit...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Ther
मुख्य लेखकों: Singh, Ruchira, Kuai, David, Guziewicz, Karina E, Meyer, Jackelyn, Wilson, Molly, Lu, Jianfeng, Smith, Molly, Clark, Eric, Verhoeven, Amelia, Aguirre, Gustavo D, Gamm, David M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2015
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817951/
https://ncbi.nlm.nih.gov/pubmed/26300224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.141
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