Mesenchymal Stromal Cells for Linked Delivery of Oncolytic and Apoptotic Adenoviruses to Non-small-cell Lung Cancers

Oncolytic adenoviruses (OAdV) represent a promising strategy for cancer therapy. Despite their activity in preclinical models, to date the clinical efficacy remains confined to minor responses after intratumor injection. To overcome these limitations, we developed an alternative approach using the c...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Ther
Auteurs principaux: Hoyos, Valentina, Del Bufalo, Francesca, Yagyu, Shigeki, Ando, Miki, Dotti, Gianpietro, Suzuki, Masataka, Bouchier-Hayes, Lisa, Alemany, Ramon, Brenner, Malcolm K
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817892/
https://ncbi.nlm.nih.gov/pubmed/26084970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.110
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