Mesenchymal Stromal Cells for Linked Delivery of Oncolytic and Apoptotic Adenoviruses to Non-small-cell Lung Cancers

Oncolytic adenoviruses (OAdV) represent a promising strategy for cancer therapy. Despite their activity in preclinical models, to date the clinical efficacy remains confined to minor responses after intratumor injection. To overcome these limitations, we developed an alternative approach using the c...

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Vydáno v:Mol Ther
Hlavní autoři: Hoyos, Valentina, Del Bufalo, Francesca, Yagyu, Shigeki, Ando, Miki, Dotti, Gianpietro, Suzuki, Masataka, Bouchier-Hayes, Lisa, Alemany, Ramon, Brenner, Malcolm K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817892/
https://ncbi.nlm.nih.gov/pubmed/26084970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.110
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