Mesenchymal Stromal Cells for Linked Delivery of Oncolytic and Apoptotic Adenoviruses to Non-small-cell Lung Cancers

Oncolytic adenoviruses (OAdV) represent a promising strategy for cancer therapy. Despite their activity in preclinical models, to date the clinical efficacy remains confined to minor responses after intratumor injection. To overcome these limitations, we developed an alternative approach using the c...

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Bibliografski detalji
Izdano u:Mol Ther
Glavni autori: Hoyos, Valentina, Del Bufalo, Francesca, Yagyu, Shigeki, Ando, Miki, Dotti, Gianpietro, Suzuki, Masataka, Bouchier-Hayes, Lisa, Alemany, Ramon, Brenner, Malcolm K
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817892/
https://ncbi.nlm.nih.gov/pubmed/26084970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.110
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