Mesenchymal Stromal Cells for Linked Delivery of Oncolytic and Apoptotic Adenoviruses to Non-small-cell Lung Cancers

Oncolytic adenoviruses (OAdV) represent a promising strategy for cancer therapy. Despite their activity in preclinical models, to date the clinical efficacy remains confined to minor responses after intratumor injection. To overcome these limitations, we developed an alternative approach using the c...

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Detalles Bibliográficos
Publicado en:Mol Ther
Main Authors: Hoyos, Valentina, Del Bufalo, Francesca, Yagyu, Shigeki, Ando, Miki, Dotti, Gianpietro, Suzuki, Masataka, Bouchier-Hayes, Lisa, Alemany, Ramon, Brenner, Malcolm K
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817892/
https://ncbi.nlm.nih.gov/pubmed/26084970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.110
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