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Determination of N-linked glycosylation in viral glycoproteins by negative ion mass spectrometry and ion mobility

Glycan analysis of virion-derived glycoproteins is challenging due to the difficulties in glycoprotein isolation and low sample abundance. Here, we describe how ion mobility mass spectrometry can be used to obtain spectra from virion samples. We also describe how negative ion fragmentation of glycan...

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Bibliografiska uppgifter
I publikationen:Methods Mol Biol
Huvudupphovsmän: Bitto, David, Harvey, David J., Halldorsson, Steinar, Doores, Katie J., Pritchard, Laura K., Huiskonen, Juha T., Bowden, Thomas A., Crispin, Max
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817836/
https://ncbi.nlm.nih.gov/pubmed/26169737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2874-3_7
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