Variable Virulence and Efficacy of BCG Vaccine Strains in Mice and Correlation With Genome Polymorphisms

Bacille Calmette–Guérin (BCG), an attenuated strain of Mycobacterium bovis, is the only vaccine available for tuberculosis (TB) control. However, BCG is not an ideal vaccine and has two major limitations: BCG exhibits highly variable effectiveness against the development of TB both in pediatric and...

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Dades bibliogràfiques
Publicat a:Mol Ther
Autors principals: Zhang, Lu, Ru, Huan-wei, Chen, Fu-zeng, Jin, Chun-yan, Sun, Rui-feng, Fan, Xiao-yong, Guo, Ming, Mai, Jun-tao, Xu, Wen-xi, Lin, Qing-xia, Liu, Jun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817822/
https://ncbi.nlm.nih.gov/pubmed/26643797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.216
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