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Novel genome polymorphisms in BCG vaccine strains and impact on efficacy

Bacille Calmette-Guérin (BCG) is an attenuated strain of Mycobacterium bovis currently used as a vaccine against tuberculosis. Global distribution and propagation of BCG has contributed to the in vitro evolution of the vaccine strain and is thought to partially account for the different outcomes of...

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Bibliografiska uppgifter
Huvudupphovsmän: Leung, Andrea S, Tran, Vanessa, Wu, Zuowei, Yu, Xuping, Alexander, David C, Gao, George Fu, Zhu, Baoli, Liu, Jun
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553098/
https://ncbi.nlm.nih.gov/pubmed/18793412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-413
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