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Curcumin Micelles Remodel Tumor Microenvironment and Enhance Vaccine Activity in an Advanced Melanoma Model

Previously, we have reported a lipid-based Trp2 peptide vaccine for immunotherapy against melanoma. The suppressive immune microenvironment in the tumor is a major hurdle for an effective vaccine therapy. We hypothesized that curcumin (CUR) would remodel the tumor microenvironment to improve the vac...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther
Prif Awduron: Lu, Yao, Miao, Lei, Wang, Yuhua, Xu, Zhenghong, Zhao, Yi, Shen, Youqing, Xiang, Guangya, Huang, Leaf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817807/
https://ncbi.nlm.nih.gov/pubmed/26334519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.165
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