Curcumin Micelles Remodel Tumor Microenvironment and Enhance Vaccine Activity in an Advanced Melanoma Model

Previously, we have reported a lipid-based Trp2 peptide vaccine for immunotherapy against melanoma. The suppressive immune microenvironment in the tumor is a major hurdle for an effective vaccine therapy. We hypothesized that curcumin (CUR) would remodel the tumor microenvironment to improve the vac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther
Hauptverfasser: Lu, Yao, Miao, Lei, Wang, Yuhua, Xu, Zhenghong, Zhao, Yi, Shen, Youqing, Xiang, Guangya, Huang, Leaf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817807/
https://ncbi.nlm.nih.gov/pubmed/26334519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.165
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