Tumor-targeted delivery of sunitinib base enhances vaccine therapy for advanced melanoma by remodeling the tumor microenvironment

Development of an effective treatment against advanced tumors remains a major challenge for cancer immunotherapy. We have previously developed a potent mannose-modified lipid calcium phosphate (LCP) nanoparticle (NP)-based Trp2 vaccine for melanoma therapy, but because this vaccine can induce a pote...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Huo, Meirong, Zhao, Yan, Satterlee, Andrew Benson, Wang, Yuhua, Xu, Ying, Huang, Leaf
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222779/
https://ncbi.nlm.nih.gov/pubmed/27863995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.11.013
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