The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma

Using in silico analysis of The Cancer Genome Atlas (TCGA), we identified microRNAs associated with glioblastoma (GBM) survival, and predicted their functions in glioma growth and progression. Inhibition of two “risky” miRNAs, miR-148a and miR-31, in orthotopic xenograft GBM mouse models suppressed...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Wong, Hon-Kit Andus, Fatimy, Rachid El, Onodera, Courtney, Wei, Zhiyun, Yi, Ming, Mohan, Athul, Gowrisankaran, Sindhuja, Karmali, Priya, Marcusson, Eric, Wakimoto, Hiroaki, Stephens, Robert, Uhlmann, Erik J, Song, Jun S, Tannous, Bakhos, Krichevsky, Anna M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817797/
https://ncbi.nlm.nih.gov/pubmed/25903473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.72
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