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Therapeutic potential of targeting microRNA‐10b in established intracranial glioblastoma: first steps toward the clinic
Abstract MicroRNA‐10b (miR‐10b) is a unique oncogenic miRNA that is highly expressed in all GBM subtypes, while absent in normal neuroglial cells of the brain. miR‐10b inhibition strongly impairs proliferation and survival of cultured glioma cells, including glioma‐initiating stem‐like cells (GSC)....
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| Autori principali: | , , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Nature
2016-02-01
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| Serie: | EMBO Molecular Medicine |
| Soggetti: | |
| Accesso online: | https://doi.org/10.15252/emmm.201505495 |
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