Bioengineering Thymus Organoids to Restore Thymic Function and Induce Donor-Specific Immune Tolerance to Allografts

One of the major obstacles in organ transplantation is to establish immune tolerance of allografts. Although immunosuppressive drugs can prevent graft rejection to a certain degree, their efficacies are limited, transient, and associated with severe side effects. Induction of thymic central toleranc...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Fan, Yong, Tajima, Asako, Goh, Saik Kia, Geng, Xuehui, Gualtierotti, Giulio, Grupillo, Maria, Coppola, Antonina, Bertera, Suzanne, Rudert, William A, Banerjee, Ipsita, Bottino, Rita, Trucco, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817796/
https://ncbi.nlm.nih.gov/pubmed/25903472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.77
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