Compromised central tolerance of ICA69 induces multiple organ autoimmunity

For reasons not fully understood, patients with an organ-specific autoimmune disease have increased risks of developing autoimmune responses against other organs/tissues. We identified ICA69, a known β-cell autoantigen in Type 1 diabetes, as a potential common target in multi-organ autoimmunity. NOD...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Fan, Yong, Gualtierotti, Giulio, Tajima, Asako, Grupillo, Maria, Coppola, Antonina, He, Jing, Bertera, Suzanne, Owens, Gregory, Pietropaolo, Massimo, Rudert, William A., Trucco, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704797/
https://ncbi.nlm.nih.gov/pubmed/25088457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2014.07.001
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