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Barrier Function of the Repaired Skin Is Disrupted Following Arrest of Dicer in Keratinocytes

Tissue injury transiently silences miRNA-dependent posttranscriptional gene silencing in its effort to unleash adult tissue repair. Once the wound is closed, miRNA biogenesis is induced averting neoplasia. In this work, we report that Dicer plays an important role in reestablishing the barrier funct...

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Vydáno v:Mol Ther
Hlavní autoři: Ghatak, Subhadip, Chan, Yuk Cheung, Khanna, Savita, Banerjee, Jaideep, Weist, Jessica, Roy, Sashwati, Sen, Chandan K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817784/
https://ncbi.nlm.nih.gov/pubmed/25896246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.65
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