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Barrier Function of the Repaired Skin Is Disrupted Following Arrest of Dicer in Keratinocytes

Tissue injury transiently silences miRNA-dependent posttranscriptional gene silencing in its effort to unleash adult tissue repair. Once the wound is closed, miRNA biogenesis is induced averting neoplasia. In this work, we report that Dicer plays an important role in reestablishing the barrier funct...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Ghatak, Subhadip, Chan, Yuk Cheung, Khanna, Savita, Banerjee, Jaideep, Weist, Jessica, Roy, Sashwati, Sen, Chandan K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817784/
https://ncbi.nlm.nih.gov/pubmed/25896246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.65
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