Serotype-specific Binding Properties and Nanoparticle Characteristics Contribute to the Immunogenicity of rAAV1 Vectors

The immunogenic properties of recombinant adeno-associated virus (rAAV) gene transfer vectors remain incompletely characterized in spite of their usage as gene therapy vectors or as vaccines. Molecular interactions between rAAV and various types of antigen-presenting cells (APCs), as well as the imp...

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Vydáno v:Mol Ther
Hlavní autoři: Ferrand, Maxime, Da Rocha, Sylvie, Corre, Guillaume, Galy, Anne, Boisgerault, Florence
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817752/
https://ncbi.nlm.nih.gov/pubmed/25881000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.59
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