Blocking the Adhesion Cascade at the Premetastatic Niche for Prevention of Breast Cancer Metastasis

Shear-resistant adhesion and extravasation of disseminated cancer cells at the target organ is a crucial step in hematogenous metastasis. We found that the vascular adhesion molecule E-selectin preferentially promoted the shear-resistant adhesion and transendothelial migration of the estrogen recept...

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Bibliografske podrobnosti
izdano v:Mol Ther
Main Authors: Kang, Shin-Ae, Hasan, Nafis, Mann, Aman P, Zheng, Wei, Zhao, Lichao, Morris, Lynsie, Zhu, Weizhu, Zhao, Yan D, Suh, K Stephen, Dooley, William C, Volk, David, Gorenstein, David G, Cristofanilli, Massimo, Rui, Hallgeir, Tanaka, Takemi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817749/
https://ncbi.nlm.nih.gov/pubmed/25815697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.45
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