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Blocking the Adhesion Cascade at the Premetastatic Niche for Prevention of Breast Cancer Metastasis
Shear-resistant adhesion and extravasation of disseminated cancer cells at the target organ is a crucial step in hematogenous metastasis. We found that the vascular adhesion molecule E-selectin preferentially promoted the shear-resistant adhesion and transendothelial migration of the estrogen recept...
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Publicado no: | Mol Ther |
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Main Authors: | , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817749/ https://ncbi.nlm.nih.gov/pubmed/25815697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.45 |
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