Loading...
Ligand-Enabled γ-C(sp(3))–H Olefination of Amines: En Route to Pyrrolidines
Pd(II)-catalyzed olefination of γ-C(sp(3))–H bonds of triflyl (Tf) and 4-nitrobenzenesulfonyl (Ns) protected amines is achieved. Subsequent aza-Wacker oxidative cyclization or conjugate addition of the olefinated intermediates provides a variety of C-2 alkylated pyrrolidines. Three pyridine- and qui...
Saved in:
| Published in: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817546/ https://ncbi.nlm.nih.gov/pubmed/26796676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b13462 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|