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SLO2 Channels Are Inhibited by All Divalent Cations That Activate SLO1 K(+) Channels

Two members of the family of high conductance K(+) channels SLO1 and SLO2 are both activated by intracellular cations. However, SLO1 is activated by Ca(2+) and other divalent cations, while SLO2 (Slack or SLO2.2 from rat) is activated by Na(+). Curiously though, we found that SLO2.2 is inhibited by...

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Vydáno v:J Biol Chem
Hlavní autoři: Budelli, Gonzalo, Sun, Qi, Ferreira, Juan, Butler, Alice, Santi, Celia M., Salkoff, Lawrence
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817167/
https://ncbi.nlm.nih.gov/pubmed/26823461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.709436
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