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Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter
The serotonin transporter (SERT) is an integral membrane protein that exploits preexisting sodium-, chloride-, and potassium ion gradients to catalyze the thermodynamically unfavorable movement of synaptic serotonin into the presynaptic neuron. SERT has garnered significant clinical attention partly...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817154/ https://ncbi.nlm.nih.gov/pubmed/27032980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23789 |
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