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Sodium channel β subunits: emerging targets in channelopathies

Voltage-gated sodium channels (VGSCs) are responsible for initiation and propagation of action potentials in excitable cells. VGSCs in mammalian brain are heterotrimeric complexes of α and β subunits. Originally called “auxiliary,” we now know that β subunit proteins are multifunctional signaling mo...

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Detalhes bibliográficos
Publicado no:Annu Rev Physiol
Main Authors: O’Malley, Heather A., Isom, Lori L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817109/
https://ncbi.nlm.nih.gov/pubmed/25668026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-021014-071846
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