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Sodium channel β subunits: emerging targets in channelopathies
Voltage-gated sodium channels (VGSCs) are responsible for initiation and propagation of action potentials in excitable cells. VGSCs in mammalian brain are heterotrimeric complexes of α and β subunits. Originally called “auxiliary,” we now know that β subunit proteins are multifunctional signaling mo...
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Publicado no: | Annu Rev Physiol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4817109/ https://ncbi.nlm.nih.gov/pubmed/25668026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-021014-071846 |
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