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Voltage-gated Na(+) channels: Potential for β subunits as therapeutic targets

BACKGROUND: Voltage gated Na(+) channels (VGSCs) contain a pore-forming α subunit and one or more β subunits. VGSCs are involved in a wide variety of pathophysiologies, including epilepsy, cardiac arrhythmia, Multiple Sclerosis, periodic paralysis, migraine, neuropathic and inflammatory pain, Huntin...

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Bibliografiske detaljer
Main Authors: Brackenbury, William J., Isom, Lori L.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376311/
https://ncbi.nlm.nih.gov/pubmed/18694383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.12.9.1191
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