Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited

The biosynthetic pathway of peptidoglycan, an essential component of bacterial cell wall, is a well-recognized target for antibiotic development. Peptidoglycan precursors are synthesized in the bacterial cytosol by various enzymes including the ATP-hydrolyzing Mur ligases, which catalyze the stepwis...

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Publicat a:PLoS One
Autors principals: Šink, Roman, Kotnik, Miha, Zega, Anamarija, Barreteau, Hélène, Gobec, Stanislav, Blanot, Didier, Dessen, Andréa, Contreras-Martel, Carlos
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816537/
https://ncbi.nlm.nih.gov/pubmed/27031227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152075
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