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Differential nuclear staining assay for high-throughput screening to identify cytotoxic compounds

As large quantities of novel synthetic molecules continue to be generated there is a challenge to identify therapeutic agents with cytotoxic activity. Here we introduce a Differential Nuclear Staining (DNS) assay adapted to live-cell imaging for high throughput screening (HTS) that utilizes two fluo...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Cell Biochem
Hauptverfasser: LEMA, Carolina, VARELA-RAMIREZ, Armando, AGUILERA, Renato J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816492/
https://ncbi.nlm.nih.gov/pubmed/27042697
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