Development of a high throughput drug screening assay to identify compounds that protect oligodendrocyte viability and differentiation under inflammatory conditions

BACKGROUND: Newly proliferated oligodendrocyte precursor cells (OPCs) migrate and surround lesions of patients with multiple sclerosis (MS) and other demyelinating diseases, but fail to differentiate into oligodendrocytes (OLs) and remyelinate remaining viable axons. The abundance of secreted inflam...

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Bibliografiset tiedot
Julkaisussa:BMC Res Notes
Päätekijät: Lariosa-Willingham, Karen D., Rosler, Elen S., Tung, Jay S., Dugas, Jason C., Collins, Tassie L., Leonoudakis, Dmitri
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Technical Note
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024459/
https://ncbi.nlm.nih.gov/pubmed/27629829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-016-2219-8
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