Development of a high throughput drug screening assay to identify compounds that protect oligodendrocyte viability and differentiation under inflammatory conditions

BACKGROUND: Newly proliferated oligodendrocyte precursor cells (OPCs) migrate and surround lesions of patients with multiple sclerosis (MS) and other demyelinating diseases, but fail to differentiate into oligodendrocytes (OLs) and remyelinate remaining viable axons. The abundance of secreted inflam...

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Dades bibliogràfiques
Publicat a:BMC Res Notes
Autors principals: Lariosa-Willingham, Karen D., Rosler, Elen S., Tung, Jay S., Dugas, Jason C., Collins, Tassie L., Leonoudakis, Dmitri
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Technical Note
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024459/
https://ncbi.nlm.nih.gov/pubmed/27629829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-016-2219-8
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