Development of a high throughput drug screening assay to identify compounds that protect oligodendrocyte viability and differentiation under inflammatory conditions

BACKGROUND: Newly proliferated oligodendrocyte precursor cells (OPCs) migrate and surround lesions of patients with multiple sclerosis (MS) and other demyelinating diseases, but fail to differentiate into oligodendrocytes (OLs) and remyelinate remaining viable axons. The abundance of secreted inflam...

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Vydáno v:BMC Res Notes
Hlavní autoři: Lariosa-Willingham, Karen D., Rosler, Elen S., Tung, Jay S., Dugas, Jason C., Collins, Tassie L., Leonoudakis, Dmitri
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Technical Note
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024459/
https://ncbi.nlm.nih.gov/pubmed/27629829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-016-2219-8
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