Protection against SHIV Challenge by Subcutaneous Administration of the Plant-Derived PGT121 Broadly Neutralizing Antibody in Macaques

Intravascular delivery of broadly neutralizing antibodies (bnAbs) has shown promise for prevention and treatment of HIV infection. However, multiple IV administrations in geographic locations with poor accessibility to medical care have practical limitations. We have assessed the efficacy of plant-d...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Rosenberg, Yvonne J., Montefiori, David C., LaBranche, Celia C., Lewis, Mark G., Sack, Markus, Lees, Jonathan P., Jiang, Xiaoming
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816452/
https://ncbi.nlm.nih.gov/pubmed/27031108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152760
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