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Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML)
Cardiac glycosides (CGs), inhibitors of Na(+)/K(+)-ATPase (NKA), used clinically to treat heart failure, have garnered recent attention as potential anti-cancer and anti-viral agents. A high-throughput phenotypic screen designed to identify modulators of promyelocytic leukemia protein (PML) nuclear...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816303/ https://ncbi.nlm.nih.gov/pubmed/27031987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152692 |
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