TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a B-cell malignancy with a mature phenotype. In spite of its relatively indolent nature, no radical cure is as yet available. CLL is not associated with either a unique cytogenetic or a molecular defect, which might have been a potential therapeutic target. Inst...

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Vydáno v:Cell Death Dis
Hlavní autoři: Bresin, A, D'Abundo, L, Narducci, M G, Fiorenza, M T, Croce, C M, Negrini, M, Russo, G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816192/
https://ncbi.nlm.nih.gov/pubmed/26821067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.419
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