Deubiquitylating enzyme USP9x regulates radiosensitivity in glioblastoma cells by Mcl-1-dependent and -independent mechanisms

Glioblastoma is a very aggressive form of brain tumor with limited therapeutic options. Usually, glioblastoma is treated with ionizing radiation (IR) and chemotherapy after surgical removal. However, radiotherapy is frequently unsuccessful, among others owing to resistance mechanisms the tumor cells...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Wolfsperger, F, Hogh-Binder, S A, Schittenhelm, J, Psaras, T, Ritter, V, Bornes, L, Huber, S M, Jendrossek, V, Rudner, J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816183/
https://ncbi.nlm.nih.gov/pubmed/26775694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.405
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