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Deubiquitylating enzyme USP9x regulates radiosensitivity in glioblastoma cells by Mcl-1-dependent and -independent mechanisms

Glioblastoma is a very aggressive form of brain tumor with limited therapeutic options. Usually, glioblastoma is treated with ionizing radiation (IR) and chemotherapy after surgical removal. However, radiotherapy is frequently unsuccessful, among others owing to resistance mechanisms the tumor cells...

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書目詳細資料
發表在:Cell Death Dis
Main Authors: Wolfsperger, F, Hogh-Binder, S A, Schittenhelm, J, Psaras, T, Ritter, V, Bornes, L, Huber, S M, Jendrossek, V, Rudner, J
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816183/
https://ncbi.nlm.nih.gov/pubmed/26775694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.405
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