Deubiquitylating enzyme USP9x regulates radiosensitivity in glioblastoma cells by Mcl-1-dependent and -independent mechanisms

Glioblastoma is a very aggressive form of brain tumor with limited therapeutic options. Usually, glioblastoma is treated with ionizing radiation (IR) and chemotherapy after surgical removal. However, radiotherapy is frequently unsuccessful, among others owing to resistance mechanisms the tumor cells...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wolfsperger, F, Hogh-Binder, S A, Schittenhelm, J, Psaras, T, Ritter, V, Bornes, L, Huber, S M, Jendrossek, V, Rudner, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816183/
https://ncbi.nlm.nih.gov/pubmed/26775694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.405
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