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Downregulation of CDC27 inhibits the proliferation of colorectal cancer cells via the accumulation of p21(Cip1/Waf1)
Dysregulated cell cycle progression has a critical role in tumorigenesis. Cell division cycle 27 (CDC27) is a core subunit of the anaphase-promoting complex/cyclosome, although the specific role of CDC27 in cancer remains unknown. In our study, we explored the biological and clinical significance of...
Gespeichert in:
| Veröffentlicht in: | Cell Death Dis |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816181/ https://ncbi.nlm.nih.gov/pubmed/26821069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.402 |
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