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ATP-dependent activation of p21(WAF1/CIP1)-associated Cdk2 by Cdc6
When cells progressing in mid-S phase are damaged with a base-modifying chemical, they arrest in S phase long after the CHK1 checkpoint signal fades out, partly because of p53-mediated long-lasting induction of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1). We have recently found that enforce...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2290776/ https://ncbi.nlm.nih.gov/pubmed/18356301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706392105 |
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