Cytoplasmic translocation, aggregation, and cleavage of TDP-43 by enteroviral proteases modulate viral pathogenesis

We have previously demonstrated that infection by coxsackievirus B3 (CVB3), a positive-stranded RNA enterovirus, results in the accumulation of insoluble ubiquitin–protein aggregates, which resembles the common feature of neurodegenerative diseases. The importance of protein aggregation in viral pat...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Fung, G, Shi, J, Deng, H, Hou, J, Wang, C, Hong, A, Zhang, J, Jia, W, Luo, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816113/
https://ncbi.nlm.nih.gov/pubmed/25976304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.58
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