PreImplantation Factor bolsters neuroprotection via modulating Protein Kinase A and Protein Kinase C signaling

A synthetic peptide (sPIF) analogous to the mammalian embryo-derived PreImplantation Factor (PIF) enables neuroprotection in rodent models of experimental autoimmune encephalomyelitis and perinatal brain injury. The protective effects have been attributed, in part, to sPIF's ability to inhibit...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Mueller, M, Schoeberlein, A, Zhou, J, Joerger-Messerli, M, Oppliger, B, Reinhart, U, Bordey, A, Surbek, D, Barnea, E R, Huang, Y, Paidas, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816111/
https://ncbi.nlm.nih.gov/pubmed/25976303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.55
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